THE SUE BERGHOFF LBD RESEARCH FELLOWSHIP
Stanford Medicine, Poston Lab | Neurology and Neuroscience
We established a research fellowship in honor of our co-founder Sue Berghoff who has Lewy body dementia (LBD), a fatal neurodegenerative disease that affects millions of people worldwide. We are grateful to Stanford Medicine for its sustained commitment and integrated approach to dementia research, from bench to bedside.
In 2021, Stanford’s Poston Lab appointed Dr. Joseph Winer as the Sue Berghoff LBD Research Fellow. He is focused on developing novel markers of Lewy body dementia.“We are looking at the relationships between data from four research areas: cognitive and behavioral assessments, brain imaging, blood and cerebrospinal fluid samples, and sleep-wake actigraphy measures.
“A common symptom of LBD is fluctuating cognition, behavior, and activity, which can change from moment to moment, hour to hour, or throughout a 24-hour cycle. Understanding the cause of these fluctuations will help us to better understand LBD onset and progression to support discovery and development of treatments and ultimately, to find a cure.”
For his PhD at UC Berkeley, Dr. Winer combined sleep physiology measures with molecular brain imaging to investigate how specific markers of sleep disruption are related to changes in the brain in healthy older adults. Based on his background in sleep research, Dr. Winer will also examine how disrupted sleep and daytime function may worsen symptoms of LBD.
Poston Lab leverages Stanford’s research infrastructure (including the Alzheimer’s disease Research Center and the Pacific Udall Center for Excellence in Parkinson’s Research) for in-depth clinical, biological, and imaging data on people with Alzheimer’s disease, Parkinson’s disease and Lewy body disease, and older adults with no neurological problems.
Dr. Kathleen Poston, MD, MS
ASSOCIATE PROFESSOR OF NEUROLOGY AND, BY COURTESY, OF NEUROSURGERY, STANFORD UNIVERSITY MEDICAL CENTER – Neurology & Neurological Sciences
Dr. Frank Longo, MD, PhD
GEORGE E. AND LUCY BECKER PROFESSOR IN MEDICINE AND PROFESSOR, BY COURTESY, OF NEUROSURGERY, STANFORD UNIVERSITY MEDICAL CENTER – Neurology & Neurological Sciences